RCMP say traffic on Highway 23 near Barons, Alta. has resumed as of early this afternoon.
A Canadian Pacific Rail train had an engine derail at 9:30 a.m. Wednesday and some empty fuel cars tipped over.
Police have said diesel fuel was leaking from an entry point.
Fire crews, CP Rail and hazardous materials response teams from Calgary were called to the scene.
No injuries were reported in the derailment.